Symptoms
- sudden onset of fever, headache, joint and muscle pain, followed by sore throat,
diarrhea, abdominal pain, vomiting and rash.
- after 3 to 5 days of fever, hemorrhagic manifestations begin.
- case fatality rate for Marburg virus infection is 25 %
- case fatality rates for Ebola infection have ranged from 50 to 90%.
Infectious agent
- Ebola virus
- Marburg virus
Mode of transmission
- close contact with infected persons or infected blood, tissues, secretions or
excretions.
- transplacental and veneral transmissions have occured.
- possibly contact with infected animal vectors (primates).
Distribution
Ebola
- epidemics have taken place in Sudan & Zaire; virus may be endemic in other parts of Africa; monkeys infected with an Ebola-like virus were imported to the US from the Philippines in 1989 (no human illness resulted).
Marburg
- scattered human cases have occurred in Central, eastern and southeastern Africa; cases reported in Germany were from infected African green monkeys imported from Uganda.
Incubation period & communicability
- for both virus infections, 5 to 10 days.
- both viruses can persist in humans for at least 2 months.
Treament
Thanks to the World Health Organisation for much of this information.
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